Harris Health is advancing plans for a new freestanding cancer center at the John M. O’Quinn Hospital campus in northeast Houston, adding a significant healthcare-focused project to the area. The facility is planned as part of the broader redevelopment anchored by the new O’Quinn Hospital, which is described as the centerpiece of Harris Health’s long-running strategic facilities plan.
The cancer center is scheduled to open in 2029, following the debut of the new O’Quinn Hospital. Harris Health reports that the total project cost for the cancer center has increased to $150 million, up from an earlier estimate of $70 million. The expanded budget reflects a larger and more comprehensive facility than originally envisioned for the site.
Planned as a four-story building, the cancer center is expected to encompass 125,000 square feet. The project will be located at the southeast corner of the O’Quinn Hospital campus on Lockwood Street in northeast Houston, establishing a dedicated space for cancer-related services adjacent to the new hospital. Construction on the cancer center is anticipated to begin in the fourth quarter of 2027, positioning the project on a multi-year development timeline.
Harris Health notes that an additional $80 million needed to realize the enlarged cancer center plan will be sourced from philanthropic support. This incremental funding supplements the system’s broader capital program and enables an upgraded scope for the facility beyond the initial $70 million concept.
The cancer center is one component of Harris Health’s wider strategic facilities plan, which is largely underpinned by a $2.5 billion bond program approved by county voters in 2023. That bond financing supports a multi-asset expansion and modernization initiative across the health system’s real estate footprint.
At the core of that plan is the new John M. O’Quinn Hospital itself, described as a 12-story, 1.3 million-square-foot facility with a total project cost of $2 billion. The hospital and the freestanding cancer center together represent a substantial concentration of healthcare investment on the Lockwood Street campus, with the cancer center adding specialized space that complements the larger inpatient and acute care capacity of the new hospital.
With defined project sizing, location and capital outlay, the cancer center marks a significant planned addition to the region’s healthcare infrastructure, aligned with the long-term facilities strategy Harris Health is executing under its bond-funded capital program and supported in part by philanthropic contributions.


